Loading up trait ala GA, by dropping the combo, is very important now imo. If there's a certain matchup where the opponent is running away like crazy (GL, Raven, DS, and Sinestro come to mind), ending with 21 xx load or f21 xx load is necessary. With a full trait loaded, we can threaten them to stop chucking shit at us, since we can punish every option they have with 28% unclashable damage or a single shot if we don't have meter, ultimately letting us get in there.
And if we're feeling extra dickish, there's the meaty pump shot setup that guarantees either 7% chip damage or 16% if the opponent tries waking up through it. It's not as viable, since there are a ton of wakeups that can go right through the pump shot, like Batman or KF's slide, but it's another option nonetheless.