I will not be sad or mad if any of these doesn't happen, but I will be full of joy if the following will happen.
Mechanics:
1) Must have the Variation System again, only now with 2 Variation per character, and try to make each Variation as different as possible, unless if it's like Reptile in MKX in which the Variations are already very versatile in gameplay. Also every returning character from MKX should have one Variation that is identical to the one in MKX but with some minor tweaks (just like the returning characters for IJ2) and one Variation that is completely new. For example having Reptile get the Noxious Variation back but then bring another entirely new Variation as well.
2) Take out the run button but keep the stamina, and replace the run mechanic with the Air Escape mechanic from IJ2, and make it work that each time you do it it costs one bar of stamina (for the record i don't have a problem with the run button though).
3) Intractables should work the same as MKX.
4) Armored moves should just be like in MKX after the final patch. In other words they should be in the game, and you can have armored launchers but only if the character is using another resource like a second meter bar.
5) Meter system should work just like in MKX with Kombo Breakers and X-Rays.
6) Each character should have 2 X-Rays with each X-Ray being exclusive to one Variation, and each X-Ray must have different animation, overall damage and damage scaling, and attack properties.
7) In addition to Variation exclusive X-Rays, bring also Variation exclusive Fatalities, with each character having one universal Fatality, one stage Fatality, and one Fatality for each Variation.
8) This is not mandatory, but it will be cool if the bring the Brutalities again with each character having one or two universal Brutalities and one Brutality for each Variation.
9) Another one that isn't mandatory but will still be cool, bring back the Friendships. We didn't see them since MKT.
10) Now this one is mandatory: Keep the Block button!
As for the roster, that's the roster I would like to see considering the characters I personally wanna have and also would make sense due to the direction of the story and potential story directions due the character endings in MKX' Arcade mode, including DLC:
Returning characters:
1) Reptile
2) Scorpion
3) Sub-Zero
4) Raiden
5) Liu Kang
6) Kitana
7) Kung Lao
8) Ermac
9) Cassie Cage
10) Takeda
11) Kenshi
12) Kotal Kahn
13) D'Vorah
14) Erron Black
15) Ferra/Torr
16) Rain
17) Jade
18) Noob Saibot
19) Frost
20) Bo' Rai Cho
21) Triborg
22) Fujin
23) Nitara
24) Goro
25) Deagon
26) Taven
27) Shang Tsung
28) Quan Chi
29) Sindel
30) Havik
31) Sheeva
32) Reiko
Also have 4 newcomers, one of them should be Kano's son.
Also have 4 guest characters and two of them should be Spawn and the Joker from IJ2 (also make him fight like in IJ2 but with attack buttons that fit the MK style).
Also my ideal list of game modes will be:
1) Arcade Mode
2) Story Mode (if it's like in IJ2 that will be nice)
3) Customization mode just like in IJ2, but will only focus on the look, no stats or hidden abilities. But now you can make each Variation to look exactly the way you want
4) An MKA Konquest-like mode of which you pick a character and go in like 3-4 levels (not to many) to gain more customization pieces and other cool stuff.
5) The Krypt, just like in MKX.
6) Online modes just like in MKX (Tower Battle, Survival KOTH, and Team Battle) along with the usual stuff.
There you have it