First, it's all about spacing my friend. B12 at a range where quick pokes can be whiff punished or d1/3/4 to continue pressure if they don't have a good 7 frame poke or try an advancing string. B1 into throw, d1/3/4, or whatever other frame trap when they're hesitant to let go of block because of 2. Even b12xx sai works to prolong your turn, because again, they'll be hesitant to let go of block due to the sai, use that opportunity to go in. Sai is also only -8 now so it's relatively safe, especially if your throw it out every now and again. The opponent would have to really be hunting for it, plus they'd need a quick reversal to catch it.
Once you dominate neutral with b1(2), Mileena has free reign of that space so get creative with your pressure. Do they want to press buttons in your face continually? Whiff punish, frame trap or just block to gauge what they're doing. Delay their buttons? Rush them down. Back off? Push them into the corner for space advantage. Jump out? Anti-air. It's all about micro-reads. Yes, you're not going to guess what they're going to do everytime, or even half the time, heck you may even guess wrong entirely and get punished, so setup that opportunity to open up your opponent when it matters most. Stay patient, keep your nerves, and make it count.
In the previous version Mileena could go ham with b12 pressure because it was +2 on block, now you have to anticipate what your opponent may do to continue pressure. It's +20ish on hit so use that time to run up and frame trap, or if you have the reactions hit confirm into roll, optimized, meterless, damage is 34% if I'm not mistaken. With that said , don't shy away from f1, 12(3), all of which are +2 on block.
