I'll be happy as long as the game provides a series of unique doors for which I shall require a distinct set of thematic keys. In other words, I appreciate backtracking and thoroughly exploring a central area. The REmake will always be my favorite, but I did genuinely enjoy RE4. I just hope they dial back the Rambo they fed us in RE5.
On a side note, did anyone play Revelations on the 3DS? It's not a stretch to assume RE6 will follow Revelations' approach to gameplay. In Rev, the gameplay changes from run and gun to a more conventional survival horror experience as you change characters. Unfortunately, the survival horror segments in that game were entirely too linear; however, with a game the size of RE6, I don't assume this will be a problem.
REVELATIONS SPOILERS
Also, by playing Revelations it adds clarity to the RE6 trailer. That "bitch" Chris was referring to is almost certainly Jess. Should be an interesting story arc.