No, he can't. But smoke bombs wreck Freddy's zoning game. You can't throw any fireballs. You can't enter NMS. You can't really do spikes either. It's best to fight Smoke at mid range, outside of his overhead (b+2) range, where you can look to whiff punish his pokes with mid spike. Smoke bomb is somewhat risky to use at this range because you can jump in on him. You can also mid spike him because the mid spike is faster than the smoke bomb. In my opinion, Smoke is Freddy's most difficult match up. I've played KT Smith and xSmokex. I do well, but I can't beat them.
In order of easiest to hardest, I would say the following are Freddy's difficult (note: not necessarily bad) match ups.
- Mileena
- Kung Lao
- Kabal
- Smoke
I am not sure what to think of Raiden since no one uses him any more. Everyone here in Ohio has stopped using the character.