KOF has ambiguous cross ups. There are hits that you can do that change the placement of the hit. But your opponent can see the attack you have chosen and block accordingly if they know where it will land. SFV has ambiguous cross ups. Gief can dive on you and depending on when he attacks and how close he is he can cross you up. But he can't chose which side it will land. So you can see if he is close enough that he can cross you up. And you can pay attention to when his attack comes out and you can assume it will cross up and block accordingly. It takes time to get that down and you are a great player to get it. But against a scrubby Gief player who is using that cross up technique you can assume what will happen and play accordingly.
In Injustice 2 you can chose where the hit will land. And your character shows no sign of it. You press one button and the hit comes out and it lands in the front. You press the other button and the hit comes out and lands in the back. Your character has the exact same animation and as the opponent they have no clue where it will land. It is purely a guessing game. Or a hard read if you really want to look at it that way. But if it was put in on purpose or it is a glitch in the matrix, it is going to ruin the game. Because there is nothing the opponent can do about it. A normal 50/50 mixup can be dealt with. this can't.
Sorry, but many 2d games have cross-ups that are a pure 50/50 guess. All 50/50's are technically a guess. In SFV there are characters that can push one button to cross up and another to not cross-up and there is no way to react to either one. This is not a valid complaint.
If the only way to block was by blocking left then right very quickly (like a hard to blockable in MKX), or if a jump in became unblockable for some reason, then I'd be on your side. Simply having an ambiguous cross up is not broken unless it's like a meterless loopable situation that does like 25% damage each time. Maybe it's too much for Supergirl to have with all her other tools, but an ambiguous cross-up is not, in itself, broken.