Tom Brady wasnt the creator of time outs of playing lame, but his style of play and sub zeros patient cautious playstyle both compliment it.
When i pick up new games my first instinct is to pick a heavy zoning/keepaway character/team and play as lame as possible. Its easy to utilize but hard to master, and you dont need to learn giant combos to sit on a life lead.
Characters like smoke and freddy who can move backwards faster than the opponent can chase them seem to have this down, and can really frustrate an opponent who is down on life and has to start taking risks just to catch you.
Sindel, sektor, noob, kitana, kabal, kano and stryker can do this fairly well with their projectile based attacks, and annoy people who are trying to get in on you, however you have no real "escape" move that will give you a speedy getaway and help you keep your own life while the opponent has to fight the clock.
Sub, kenshi, reptile and shang all have projectiles which can either send your opponent away from you, or assist in stopping them getting to you, so they are good at utilizing the clock too.
Other characters like jax and sonya have fast projectiles that arent meant for keeping people away really, but they will do it if they need to. Their fast projectile is good for trades and stopping people chucking shit at you all day, but they would still prefer to stay in on you.