Well, Street Fighter uses six attack buttons. MK only uses four. The reason I space my attacks out is so my fingers don't feel crammed in one position while I'm doing combos. The way I have mine set, it feels way more relaxed than with my attacks next to each other. But that's just me. For SF I use Top: LP, MP, HP, blank and Bottom: LK, MK, HK, blank. You'll see what best suits you when you practice more with your stick, though.