Finally someone shows the fighting game community why this concept works.
I, and several other UMK3 players play on keyboard as it is, and have for over 15 years. The buttons would function in the same pattern as UMK3 already, but the directionals, I'm not 100% sure would need to be exactly the same as the way it is for the SF layout, however having up by your thumb seems interesting as I use to put an extra Up button next to my Right button to make 720s easier on the keyboard. I'm not sure how Run would deal when having to sometimes use your right thumb for up, but it might never be necessary.