1) It does NOT work on Goro. If you want to extend damage on Goro, just do F12B2 DF2 MB into whatever else.
2) For the rest of the cast (both males and females), don't change things specifically for males and females (complicate your life) and try to do the following, which is universal for both males and females.
3) If your string starter F1 starts at point blank, i.e, right next to the opponent, keep in mind that the run distance on the 2nd RC is a bit LONGER than the 1st RC. The 1st RC is very short. Just practice F12B2 (1st RC) F1. Get the feel for what's the shortest distance you had to run to get the F1 to connect. Then practice F12B2 (1st RC), F12B2 (2nd RC) F1. Get the feel for what's the distance you had to run for the 3rd F12B2 to connect.
4) If your string starter F1 does NOT start at point blank distance from opponent, it gets a bit shaky and you will have to do F12B2, F12B2, F12 BF3 (sacrifice the 3rd chain's B2) for 28%. Hence, If you're barely punishing without meter an opponent's attack that had some pushback, you only get 28%. On the bright side, you can use a bar of meter and do F12B2, F12B2, DF2 MB, B14 BF3 (or B1... 1+3) for 36%.